Analysing Ribosome Profiling data

[dena.dinesh]

Hi

I would like to know of any tool/package for analyzing the Ribosome profiling data(Translatome data). Is there any protocol I can follow for analysing the RBP data. Please guide me

[PolPittacus7]

Hi dena,

I work a bit with ribosome profiling data informatics, so I may be of some help. Can you clarify what specifically interests you, in terms of downstream analyses? Do you want to have visualisation of RPF's mapping to a given transcript, a graph that shows translatome wide framing distribution or transcript specific framing distribution, differential expression analyses of translation/post-transcriptional activity, etc.?

Let me know and I'll see how I can help! Best wishes