If you do happen to perform such a comparison, please do post a link to it here and/or on biostars, since I expect many people would find it interesting.
-
-
Why not download a real data set from NCBI and then randomly sample from that to derive pseudo-data sets of varying read depths? That way you would have an realistic baseline to compare to.Originally posted by Zimbobo View PostMichael Black, Ph.D.
ScitoVation LLC. RTP, N.C.Comment
-
Note that the person you're replying to posted that ~4 years ago...Originally posted by mbblack View PostComment
-
NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...Today, 06:46 AM -
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
Comment