Thank you, syfo!
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Similar problem
I was facing a similar problem with rmdup of picard and samtools.
After performing 'rmdup', picard left `~23,000' reads whereas samtools left me with '~1800' reads only, which is a huge difference.
Anyhoo, this thread explained a lot... So thank you everyone who has contributed.
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Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing...
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