[GenoMax]

Thank you very much for your kind reply. Here is my bash_profile file:# .bash_profile

# Get the aliases and functions
if [ -f ~/.bashrc ]; then
. ~/.bashrc
fi

# User specific environment and startup programs

PATH=$PATH:$HOME/.local/bin:$HOME/bin

export PATH


I am not sure which part I need to edit. I have different tools in different directory, like:

/home/zillur/Desktop/zillur/Tools/bcftools-1.2

/home/zillur/Desktop/zillur/Tools/samtools-1.2

/home/zillur/Desktop/zillur/Tools/bowtie2-2.2.5

If the executables that you want to run are directly under those top level directories then you would need to edit the PATH line like so:

PATH=$PATH:$HOME/.local/bin:$HOME/bin:/home/zillur/Desktop/zillur/Tools/bcftools-1.2:/home/zillur/Desktop/zillur/Tools/samtools-1.2:/home/zillur/Desktop/zillur/Tools/bowtie2-2.2.5

BTW: what do you see when you do

$ echo $HOME

[zillur]

Thank you very much for your kind suggestions. After editing the bash_profile my system is working perfectly and I can run all the tools. Now I want to allow other users to use this tools. How can I manage it.

Best Regards
Zillur