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  • cross correlation for paired-end ChIP-seq

    Would this still be a useful tool to assess ChIP quality? If I understand correctly, this is used for single end experiments because it is necessary to estimate the fragment size (but unnecessary since paired-end data gives you exact fragment size).

    Has anyone computed this anyway with paired-end data as a measure for how well your IP worked? If so, would simply using either R1 or R2 of each pair be a reasonable approach?

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  • seqadmin
    Recent Developments in Metagenomics
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    Metagenomics has improved the way researchers study microorganisms across diverse environments. Historically, studying microorganisms relied on culturing them in the lab, a method that limits the investigation of many species since most are unculturable1. Metagenomics overcomes these issues by allowing the study of microorganisms regardless of their ability to be cultured or the environments they inhabit. Over time, the field has evolved, especially with the advent...
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