I have merged VCF files of every individuals of a particular population using VCF merge. But I am not sure which SNP is coming from which individual. I tried to convert the merged VCF file in PGDSpider to generate GENEPOP format data to use in Lositan for Outlier detection. However, Lositan only detects one population. What could be the best way to merge different VCF files for different populations into one Genepop file to use in Lositan for Outlier detection?
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM -
Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing...