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I have merged VCF files of every individuals of a particular population using VCF merge. But I am not sure which SNP is coming from which individual. I tried to convert the merged VCF file in PGDSpider to generate GENEPOP format data to use in Lositan for Outlier detection. However, Lositan only detects one population. What could be the best way to merge different VCF files for different populations into one Genepop file to use in Lositan for Outlier detection?
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The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...Today, 07:48 AM -
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM