I am new to bam file. I was using dosage data of genotypes to do association test (each column represent a snp, and each row represent an individual). Is it possible to convert bam file to this kind of file?
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You can use the bam files as input to a program that does genotype calling, like GATK, for example.
https://www.broadinstitute.org/gatk/
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification,...10-30-2026, 06:46 AM
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