Annotate peaks based on Histon Mark

[Jennifer_Rdn]

Hi everyone,

I've performed ChIP-seq analysis on TFs for a specific cell line for which I only have three histones marks (H3K4me1, H3K27ac and H3K4me3). I used HOMER to annotate differents peak from my datas but now I would like to use these histones marks to improve the annotation (for example if one peak is present as the same region than H3K27ac and H3K4me1 peaks, I would like to say that this region is an active enhancer).

Does somebody have already done this kind of analysis?

Thanks in advance,

[GenoMax]

For reference, cross-posted: https://www.biostars.org/p/186058/