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  • ea11
    Member
    • Jun 2015
    • 36

    #1

    Ensembl miRNA host genes

    tmiI have been using a GTF file from Ensembl to get count table from HTSeq for an RNAseq experiment. Tables were inputted into DESeq2 and the resulting DE genes include microRNA host genes (e.g. mir34HG).

    Does anyone know what these host genes are? Are they equivalent to pre-miRNAs or are they seperate transcripts?

    I am struggling to get information about what these host genes are. I understand they they are where the miRNAs originate (e.g. in the intron of a gene, etc), but they are forming separate transcripts.

    Any help on this would be much appreciated
    Thanks
  • GenoMax
    Senior Member
    • Feb 2008
    • 7142

    #2
    Someone more knowledgeable is bound to come along but in the mean time take a look at this paper: http://genome.cshlp.org/content/14/10a/1902.full

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    • ea11
      Member
      • Jun 2015
      • 36

      #3
      Originally posted by GenoMax View Post
      Someone more knowledgeable is bound to come along but in the mean time take a look at this paper: http://genome.cshlp.org/content/14/10a/1902.full
      Thanks GenoMax, I'll have a look at the paper while I wait to see if anyone else know more about them.

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