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I'm looking at two homeologs and trying to gain information about their potentially different evolutionary rates. There is a publicly available dataset in the form of a VCF file from whole genome sequencing of many different, diverse cultivars. Is there a way to get nucleotide diversity (and calculate for coding sequence, synonymous, nonsynonymous etc) or Ka/Ks values for the two paralogs?
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Technological advances have led to drastic improvements in the field of precision medicine, enabling more personalized approaches to treatment. This article explores four leading groups that are overcoming many of the challenges of genomic profiling and precision medicine through their innovative platforms and technologies.
Somatic Genomics
“We have such a tremendous amount of genetic diversity that exists within each of us, and not just between us as individuals,”...05-24-2024, 01:16 PM -
The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...05-06-2024, 07:48 AM