Hello all,
I see that Velvet has a Columbus module to assemble genomes using a reference as a template. Although it also says this is best used for transcriptome assembly and identification of breakpoints.
Has anybody used this for a genome assembly? Where one uses contigs from a de novo assembly as input against a closely related reference genome?
Thanks
I see that Velvet has a Columbus module to assemble genomes using a reference as a template. Although it also says this is best used for transcriptome assembly and identification of breakpoints.
Has anybody used this for a genome assembly? Where one uses contigs from a de novo assembly as input against a closely related reference genome?
Thanks