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  • husamia
    Member
    • Apr 2010
    • 66

    #31
    "it depends on the data in question". I suggest remove duplicates and see how it affects the overall quality. Then, decide weather removing duplicates is useful.

    Comment

    • Brian Bushnell
      Super Moderator
      • Jan 2014
      • 2709

      #32
      Assemblers use coverage to determine things like how many copies of a repeat there are and whether a base is an error or not. Removing duplicates can effect this; it could increase or decrease the quality of the assembly. Are you using PCR-amplified data?

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