Unconfigured Ad

Collapse
X
Collapse
 
  • Page of 1
  • Time
  • Show
Clear All
new posts
Previous template Next
  • nora
    Member
    • Dec 2009
    • 11
    #1

    BFAST mapping quality scores

    Dear all,

    Can anybody tell me what the BFAST mapping scores stand for? I know they go from 0-255 but I wonder how they are computed; and do they have anything to do with the probability of a false positive?
    Tags: None
    • nilshomer
      Nils Homer
      • Nov 2008
      • 1283
      #2
      Originally posted by nora View Post
      Dear all,

      Can anybody tell me what the BFAST mapping scores stand for? I know they go from 0-255 but I wonder how they are computed; and do they have anything to do with the probability of a false positive?
      See the following link for an discussion of how BFAST calculates mapping quality:
      Blat-like Fast Accurate Search Tool
      https://sourceforge.net/apps/mediawiki/bfast/index.php?title=Mapping_Quality
      Download Blat-like Fast Accurate Search Tool for free. BFAST facilitates the fast and accurate mapping of short reads to reference sequences, where mapping billions of short reads with variants is of utmost importance.


      See this link (check the supplementary materials) behind the mathematical discussion behind mapping quality:
      http://genome.cshlp.org/content/18/11/1851.abstract

        Comment

        • nora
          Member
          • Dec 2009
          • 11
          #3
          Thanks so much!

            Comment

            Previous template Next

            Latest Articles

            Collapse
            • SEQadmin2
              Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
              by SEQadmin2



              Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

              Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating              ...
              10-14-2026, 09:55 AM
            • SEQadmin2
              New Genomics Technologies Take Aim at Long-Standing Limits
              by SEQadmin2


              Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.

              We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing              ...
              09-28-2026, 10:25 AM
            View All

            ad_right_rmr

            Collapse

            News

            Collapse
            Topics Statistics Last Post
            Exeter-Led Study Maps What an Average Human Genome Looks Like by SEQadmin2
            Started by SEQadmin2, Today, 11:13 AM
            0 responses
            10 views
            0 reactions
            		 Last Post SEQadmin2
            by SEQadmin2
            Today, 11:13 AM  
            Long-Read Sequencing Uncovers Cancer Mutations Conventional Testing Missed by SEQadmin2
            Started by SEQadmin2, Today, 10:48 AM
            0 responses
            9 views
            0 reactions
            		 Last Post SEQadmin2
            by SEQadmin2
            Today, 10:48 AM  
            Mayo Clinic-Led Study Detects DNA Mutations Across Noncancerous Tissues by SEQadmin2
            Started by SEQadmin2, 10-15-2026, 10:52 AM
            0 responses
            32 views
            0 reactions
            		 Last Post SEQadmin2
            by SEQadmin2
            10-15-2026, 10:52 AM  
            Study Finds Chromatin Motion Holds Steady Until Cells Face Stress by SEQadmin2
            Started by SEQadmin2, 10-14-2026, 05:39 AM
            0 responses
            40 views
            0 reactions
            		 Last Post SEQadmin2
            by SEQadmin2
            10-14-2026, 05:39 AM  
            View All
            Working...