[HESmith]

1) Optimize your chromatin immunoprecipitation (see this reference for guidance).

2) Optimize your library prep, using same amount of input chromatin equal to the amount recovered by ChIP.

Good luck!

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Problem about samtools sort and tview, Who can help me?

Hello everyboday, I am a newbie, my sam file size is about 45,786 kB, however after I use the samtools sort command, the .bai file produced is just only 1 kb, I wander it is right. In addition, after I use the samtools tview command, the result show a line N and nothing. I don't know where the problem is, who can help me?