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  • Yasmin Lima
    Junior Member
    • Jan 2016
    • 2
    #1

    dbNFSP annotation

    Hello everyone

    I am a beginner in the next generation world.

    I have some data to analyze and I am confused about the dbNFSP database annotation...

    I can interpret very well the annotation because I can find easy information about the range scores of some algorithms, like PhyloP, LTR, MutationTaster and other. Do they range from 0 to 1, 0 to 10, or what?

    I mean, I have a value but I can interpret because I don't know which are the parameters...

    I have used Annovar, but the Annovar documentation for these algorithms is very poor in informations about.

    Anyone knows where I can find these informations, please?
    Tags: None
    • vivek_
      PhD Student
      • Jul 2012
      • 164
      #2
      You can get the descriptions from a readme file included in the dbNSFP distribution.

      Jpopgen - dbNSFP
      https://sites.google.com/site/jpopgen/dbNSFP
      Please access the current dbNSFP at dbNSFP.org. LEGACY VERSIONS (1.x - 4.x) INTRODUCTION: dbNSFP is a database developed for functional prediction and annotation of all potential non-synonymous single-nucleotide variants (nsSNVs) in the human genome. Its current version is based on the Gencode

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