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  • dmurdock
    Junior Member
    • Mar 2010
    • 9

    #1

    Samtools SNP quality

    Hi everyone. I'm attempting to find out what goes into the samtools SNP quality calculation. I've read through the MAQ paper to no avail. I imagine it involves coverage, base quality, etc. I'm comparing snps generated by other aligners like corona lite but it's difficult to compare snp quality if I don't have a grasp of how it's calculated.

    Thanks,
    David Murdock
  • nilshomer
    Nils Homer
    • Nov 2008
    • 1283

    #2
    Originally posted by dmurdock View Post
    Hi everyone. I'm attempting to find out what goes into the samtools SNP quality calculation. I've read through the MAQ paper to no avail. I imagine it involves coverage, base quality, etc. I'm comparing snps generated by other aligners like corona lite but it's difficult to compare snp quality if I don't have a grasp of how it's calculated.

    Thanks,
    David Murdock
    They are defined here:
    http://samtools.sourceforge.net/cns0.shtml

    Did you read the supplemental materials from the MAQ paper?

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