I am currently trying to create a mm10 mappability using peakseq from the code on http://info.gersteinlab.org/PeakSeq. I have gotten all the way up to creating the .hash files using the python compile, but am having issues with the next step, which is described as "use the CountMap as normal'. I'm not sure whether or not I'm supposed to run the CountMap or Map python command first and how to move on from here. Any help would be appreciated.
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM -
Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
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