Hello, could any one explain when analyzing the DNase footprint, why only the 5-prime end of the DNase-seq read is considered? Given a genomic position, if there are reads whose 3-prime could be mapped to it, why those reads were not considered as cut events? I guess the DNase-seq should NOT be strand-specific.....
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
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