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  • Jane M
    Senior Member
    • Aug 2011
    • 239

    #1

    Extracting alternate loci from fasta genome

    Dear all,

    I downloaded full reference fasta genomes for hg19, mm9 and mm10 from gencode. They include reference chromosomes, scaffolds, assembly patches and haplotypes.
    For a specific purpose, I want to remove haplotypes.
    I did not manage to find a description of the nomenclature used for the contigs in fasta file.
    In the hg19 reference genome I use, there are 297 contigs. One can see for example:
    >chr1 1
    >chr2 2
    ...
    >chrM MT
    >GL877870.2 HG1007_PATCH
    >GL877872.1 HG1032_PATCH
    ...
    >GL383545.1 HSCHR10_1_CTG2 <- is it an "unlocalized sequence" ?
    >GL383546.1 HSCHR10_1_CTG5
    ...
    >GL000191.1 GL000191.1
    >hg19GL000192.1 GL000192.1
    I would like to know how many of them are haplotypes and which ones are they.
    Is there a way to get this information?

    Thank you in advance for your help.
  • Jane M
    Senior Member
    • Aug 2011
    • 239

    #2
    If it can help someone in the future, we can get this type of information on NCBI: ftp://ftp.ncbi.nlm.nih.gov/genomes/g...ate_mammalian/
    In *_report.txt files, for each contigs, there is assembled-molecule / unlocalized-scaffold / unplaced-scaffold / novel-patch / fix-patch or alt-scaffold.

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