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  • boetsie
    Senior Member
    • Feb 2010
    • 245

    #1

    finding SV pipeline with PE reads

    Hi all,

    does anyone have a pipeline for finding structural variations on a reference genome using illumina PE reads.

    The pipeline would be something like;
    - mapping the reads to a reference (bowtie?)
    - converting the sam to bam file, and convert to SV detection input format
    - SV detection method (Pindel, Breakdancer, CNV-seq...).

    Any help on this would be great, especially since there are a lot of issues for inputs for the SV detection methods.

    Thanks in advance,
    Marten

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