Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • wurensh
    Junior Member
    • Aug 2010
    • 2

    #1

    Problem about ClonalFrame

    hi, all. In one of our projects, we use ClonalFrame to remove SNPs caused by recombination. However, when I process the output of ClonalFrame, I faced one problem:

    In the poly part of the output, I think the number should be continual, however, there appear some zeros in the sequence, such as,
    # poly
    ...
    659
    701
    0
    0
    0
    0
    0
    728
    733
    734
    735

    I don't know these zeros mean. Can anyone here help me? Many thanks.
  • wurensh
    Junior Member
    • Aug 2010
    • 2

    #2
    Thanks to Xavier, I have solved this problem.

    According to Xavier, these zeros mean that the site can't be found in the first genome. In my input data of clonalFrame, these sites use - instead of ATCG.

    Comment

    Latest Articles

    Collapse

    • SEQadmin2
      Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
      by SEQadmin2



      Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

      Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
      ...
      10-14-2026, 09:55 AM
    • SEQadmin2
      New Genomics Technologies Take Aim at Long-Standing Limits
      by SEQadmin2


      Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.

      We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing
      ...
      09-28-2026, 10:25 AM

    ad_right_rmr

    Collapse

    News

    Collapse

    Topics Statistics Last Post
    Started by SEQadmin2, Yesterday, 11:13 AM
    0 responses
    17 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, Yesterday, 10:48 AM
    0 responses
    18 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 10-15-2026, 10:52 AM
    0 responses
    36 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 10-14-2026, 05:39 AM
    0 responses
    42 views
    0 reactions
    Last Post SEQadmin2  
    Working...