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  • How to merge individual contigs

    Hi Everyone,

    I would really be thankful if anyone is able to tell me solution to the following,

    1. I have sequences some BAC clones and have generated contigs. It turns out that 2 BAC's represent same genomic regions..so I would like to merge contigs from both the sources and get larger contigs.
    2. Is there any tool whereby I can merge contigs from both the clones?

    Thanking you,

  • #2
    Maybe try the classic assembly tool PHRAP? Or do it "by hand" if it really is just 2 BACs's (in a text editor or your scripting language of choice).

    Comment


    • #3
      I'm having the same problem too...

      I've tried Phrap/CAP3/CABOG, but none of them is good enough. Or maybe I missed some important parameters?

      Anyone got a good solution?

      Comment


      • #4
        You could try an assembly editor like gap4 or gap5 for manual finishing.

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