I want to find out the mode of action of the novel compounds.
I have generated the mutants of mycobacterium using high concentrations of these compounds and got the data for whole genome sequencing. I would like to compare this data with that of the wild type and see if there are any point mutations or SNPs. If they are any mutations, on what gene or genes they are associated with.
Thanks
Kind Regards
I have generated the mutants of mycobacterium using high concentrations of these compounds and got the data for whole genome sequencing. I would like to compare this data with that of the wild type and see if there are any point mutations or SNPs. If they are any mutations, on what gene or genes they are associated with.
Thanks
Kind Regards