Is there a tool/script/algorithm for grouping sequences into bins so that within each group homology for any two sequences is above (or equal to) a certain threshold value (unless there's only one sequence in a bin)? Some sequences may end up being chimeric, some bins may end up containing a single sequence but only if they don't fit into all other bins. Asked this on biostars, but got no replies.
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
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