-
You can use samtools view -q 1 to only output uniquely mapped reads (and omit both unmapped and ambiguous ones). Ambiguous reads that can be mapped to different locations with the same score have mapping quality 0 in BWA. -
ID'ing Uniquely Mapped Regions in BWA
I have another BWA inquiry. How can one id the uniquely mapped reads from a sam/bam generated by BWA? Thanks for any thoughts.
-
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
Leave a comment: