Hi everybody,
What are the consideration in merging sequencing data from from different sequencing runs?
if data are paired-end, should it matter how close the insert sizes between each dataset that will be merged are?
Also, SAMTOOLS have a merge tool for merging BAM files, what is the difference between merging BAM files and merging fastq sequence files? Are the two methods equivalent? Or which one has advantage over the other?
Thanks.
CSoong
What are the consideration in merging sequencing data from from different sequencing runs?
if data are paired-end, should it matter how close the insert sizes between each dataset that will be merged are?
Also, SAMTOOLS have a merge tool for merging BAM files, what is the difference between merging BAM files and merging fastq sequence files? Are the two methods equivalent? Or which one has advantage over the other?
Thanks.
CSoong
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