I have to do a bioinformatic assignment and I am really interested in Rheumatoid arthritis. My assignment brief states "The choice will be yours but you will be expected to provide a detailed analysis covering your subject of interest " and "All analysis will be carried out using freely available online bioinformatics tools". Can anybody help me out with a specific analysis I could do? I have thoughts on potentially new targets/drugs but I do not know if this would really fall into the bioinformatic category? (I do not want to create a phylogenetic tree).
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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