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  • read group in SAM format

    Hi,

    Maybe this question is not so technically related. In SAM format specification, in the description of "header section" about @RG, it says:

    "Read group IDs may be modified when merging SAM files in order to handle collisions."

    Does anybody have experience about how the IDs will be changed?

    thanks for any help!

  • #2
    according to your needs. if you got to dataset being merged with different RG but are really the same you could modify it to become the same. if you got 2 dataset with same RG but actually different samples, you may modify one of them so the RG will reflect they are different.

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    • #3
      Thanks for quick reply! Now I understand, so I need to modify RG manually. The tool can not automatically change the RG.

      Comment

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