I am trying to do a de novo assembly using Trinity. Using Transdecoder and blastp/hmmscan search to do annotation (using Uniprot/pfam databases). https://github.com/TransDecoder/TransDecoder/wiki . But i would like to do a blastp/hmmscan search only for a specific taxonomy, viridiplantae to be more precise (taxid: 33090). I managed to find a Uniprot database for plants only, but my problem is how to find a pfam database specific for plants. Here : http://pfam.xfam.org/search#tabview=tab1 there is the taxonomy tab, but when checking the box "find unique.." it returns an error. Thanks in advance
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
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Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
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