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  • Rinnegan
    Junior Member
    • Apr 2020
    • 1

    #1

    Pedigree Analyis with VCF

    Hi all,

    i am currently working on a Perl-Script to detect monogenic diseses.
    My status right now is, that i have included the parents and the children via VCF-Files into the code and it works perfectly.
    My professor told me that it would be helpful too when i could include grandparents aswell.

    My problem is, that i dont really now how to include them into my VCF-Files.
    I already read soemthing about Linkage-FOrmat in VCF's, but i did not help me at all fixing my problem.

    It would be very helpful, if someone may have an idea how to properly include grandparents into a VCF-File

    thanks in advance
    rinnegan

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