Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • papori
    Senior Member
    • Dec 2010
    • 181

    #1

    Donor-Participants species probability

    Hi all,
    We are doing a microbiome study with FMT (Fecal Microbiota transplant), and I have a statistic question about something we found.

    Background
    In the experiment there are 2 donors and 11 recipients.
    Donor 1 group are 6 participants
    Donor 2 group are 5 participants

    Result of FMT
    In Donor 1 group we have 3 responders, and 3 non responders
    In Donor 2 group we have 0 responders, and 5 non responders

    We found that there is only one species that is in Donor 1 and in the 3 responders, but not found in the rest.
    We suspect that this species can be a marker for matching Donor-Participant for being a responder.
    We have 200 species in all the samples together.

    Question
    I would like to calculate the probability for this, and I believe Bayes probability is the way.
    I think that I know how to ask the question, but not to do the calculation and I will appreciate your help:

    What is the likelihood to be this species that found only in Donor 1 and in his responders, when I have only 3 responders out of 11 participants and 2 Donors?

    Thanks for the reading, and I hope to understand it ��
    Last edited by papori; 05-10-2020, 01:33 AM.

Latest Articles

Collapse

  • SEQadmin2
    Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
    by SEQadmin2



    Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

    Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
    ...
    10-14-2026, 09:55 AM
  • SEQadmin2
    New Genomics Technologies Take Aim at Long-Standing Limits
    by SEQadmin2


    Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.

    We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing
    ...
    09-28-2026, 10:25 AM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by SEQadmin2, 10-22-2026, 11:13 AM
0 responses
60 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-22-2026, 10:48 AM
0 responses
42 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-15-2026, 10:52 AM
0 responses
46 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-14-2026, 05:39 AM
0 responses
48 views
0 reactions
Last Post SEQadmin2  
Working...