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  • New repo sharing Broad production workflows for data processing & analysis

    (cross-posting from Biostars)

    Hi all, I just wanted to let people know about a new open-source repository of analysis pipelines called WARP (for WDL Analysis Research Pipelines). It's maintained by the team at the Broad Institute that develops and optimizes data processing and analysis workflows for the Broad's production pipelines, which are used for processing data from major genomics, single-cell and epigenomics projects like gnomAD, Human Cell Atlas and the BRAIN Initiative. The workflows are designed to be very robust and efficient; the Broad team primarily runs them on Google Cloud but they can also be run on local infrastructure. You can read more about the resource in this blog post.

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  • seqadmin
    Genetic Variation in Immunogenetics and Antibody Diversity
    by seqadmin



    The field of immunogenetics explores how genetic variations influence immune responses and susceptibility to disease. In a recent SEQanswers webinar, Oscar Rodriguez, Ph.D., Postdoctoral Researcher at the University of Louisville, and Ruben Martínez Barricarte, Ph.D., Assistant Professor of Medicine at Vanderbilt University, shared recent advancements in immunogenetics. This article discusses their research on genetic variation in antibody loci, antibody production processes,...
    11-06-2024, 07:24 PM
  • seqadmin
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    by seqadmin



    Next-generation sequencing (NGS) and quantitative polymerase chain reaction (qPCR) are essential techniques for investigating the genome, transcriptome, and epigenome. In many cases, choosing the appropriate technique is straightforward, but in others, it can be more challenging to determine the most effective option. A simple distinction is that smaller, more focused projects are typically better suited for qPCR, while larger, more complex datasets benefit from NGS. However,...
    10-18-2024, 07:11 AM

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