I have Illumina sequenced paired-end reads of an arthropod genome. I already mapped my reads to the reference genome and generated a BAM file and a variant call format file. Which reference based assembler should I use? I also thought to do the de novo assembly first and then use the reference to help scaffolding.
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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04-22-2024, 07:01 AM -
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