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  • cybercot
    Junior Member
    • Apr 2011
    • 1

    #1

    Calculate p-value of SNP

    How do I calculate p-value of snp if I have after counting 20 reads for letter A, 17 reads for letter C and 1 read for letter T and G. I know that in this coordinate the snp is A/C (and this is good snp), but p-value that I count is too big...

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    Reply to 16S/ITS Profiling vs. Shotgun Metagenomics: What Changes in Your Workflow?
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    16S/ITS Profiling vs. Shotgun Metagenomics: What Changes in Your Workflow?
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    NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification,...
    10-30-2026, 06:46 AM

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