I noticed this directory in the 1000 Genomes Project files today, which seems to contain sequence alignment data: ftp://ftp.1000genomes.ebi.ac.uk/vol1...ata/alignment/ . Does anyone know what the NCBI varpipe data is or what "varpipe" refers to? (Also, any idea why it's in the "technical" folder rather than the "data" folder?)
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Hi Greg
The NCBI Varpipe data is an alternative alignment set being created using the 1000 genomes data.
It is not under data as it isn't included in the official alignment release as described by the alignment index ftp://ftp.1000genomes.ebi.ac.uk/vol1...lignment.index
We are presenting it on the ftp site as this data is being used to support some of our multiple snp calling pipelines and we want users to be able to see as much of the data which goes into our pipelines as possible
If you have any other questions about the 1000 genomes data set you can always email [email protected]
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Thanks very much, Laura. I also came across this pdf which seems to provide further details on this approach: http://www.bbmriwiki.nl/raw-attachme...-20100913d.pdfComment
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM
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