Should I expect anything out of the ordinary by using a reference containing N's when aligning a paired end sample with BWA? It runs fine, which I would expect, but I wasn't sure if there were issues that I should look for in the output.
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM
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