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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,335 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,081 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by frankenndoc, 03-03-2019, 10:31 AM
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9 responses
7,783 views
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by frankenndoc
03-04-2019, 07:16 AM
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Started by ecSeq Bioinformatics, 02-23-2019, 11:28 PM
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1 response
2,963 views
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by LarsB
03-02-2019, 02:59 AM
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Started by courtnes, 02-28-2019, 05:54 AM
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0 responses
935 views
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by courtnes
02-28-2019, 05:54 AM
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Started by fznajar, 02-27-2019, 02:59 PM
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0 responses
1,159 views
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by fznajar
02-27-2019, 02:59 PM
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Started by Kulvait, 06-14-2017, 06:11 AM
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4 responses
4,396 views
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by jilguero888
02-27-2019, 09:22 AM
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Started by mafernandez, 02-27-2019, 05:32 AM
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0 responses
3,232 views
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by mafernandez
02-27-2019, 05:32 AM
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Started by caharpuka, 02-27-2019, 04:38 AM
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0 responses
2,051 views
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by caharpuka
02-27-2019, 04:38 AM
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Started by Kaizen, 02-27-2019, 12:33 AM
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0 responses
1,318 views
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by Kaizen
02-27-2019, 12:33 AM
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Started by sisterdot, 06-12-2013, 03:41 AM
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23 responses
34,728 views
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by FJwlf
02-24-2019, 09:01 AM
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Started by Ahmed, 02-23-2019, 12:42 AM
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0 responses
1,126 views
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by Ahmed
02-23-2019, 12:42 AM
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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Today, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
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Started by SEQadmin2, Today, 10:08 AM
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Today, 10:08 AM
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Started by SEQadmin2, Yesterday, 11:05 AM
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Yesterday, 11:05 AM
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Started by SEQadmin2, 07-02-2026, 11:08 AM
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07-02-2026, 11:08 AM
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