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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,627 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,243 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by bair, 03-17-2010, 02:30 AM
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3 responses
13,395 views
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by psm3426
12-23-2010, 12:00 PM
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Started by gen2prot, 12-23-2010, 09:42 AM
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0 responses
2,161 views
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by gen2prot
12-23-2010, 09:42 AM
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Started by csoong, 11-04-2010, 02:52 PM
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5 responses
4,962 views
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by yinshe
12-23-2010, 08:12 AM
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Started by yasu, 02-15-2010, 06:37 PM
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3 responses
8,567 views
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by xujie
12-23-2010, 04:55 AM
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Started by csoong, 12-20-2010, 06:39 AM
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6 responses
4,919 views
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by csoong
12-23-2010, 03:46 AM
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Started by ia_aka, 12-22-2010, 11:28 PM
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0 responses
1,916 views
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by ia_aka
12-22-2010, 11:28 PM
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Started by xinwu, 12-22-2010, 10:33 PM
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0 responses
2,719 views
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by xinwu
12-22-2010, 10:33 PM
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Started by ketan_bnf, 12-22-2010, 02:29 AM
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2 responses
2,905 views
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by ketan_bnf
12-22-2010, 10:17 PM
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Started by foxyg, 11-22-2010, 09:06 PM
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8 responses
5,117 views
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by genesquared
12-22-2010, 06:46 PM
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Started by gfmgfm, 12-22-2010, 10:35 AM
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0 responses
1,597 views
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by gfmgfm
12-22-2010, 10:35 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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12 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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12 views
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by SEQadmin2
07-23-2026, 11:41 AM
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