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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,373 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,302 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by yaximik, 12-30-2012, 07:38 AM
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50 responses
21,923 views
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by GenoMax
09-27-2015, 04:22 AM
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Started by taehee, 09-25-2015, 04:31 PM
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7 responses
3,707 views
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by taehee
09-26-2015, 08:38 PM
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Started by cmccabe, 09-23-2015, 12:17 PM
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15 responses
3,006 views
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by cmccabe
09-26-2015, 08:28 AM
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Started by Waqasuddin Khan, 09-26-2015, 03:18 AM
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2 responses
3,634 views
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Started by xiao, 09-25-2015, 07:16 AM
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4 responses
3,169 views
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by xiao
09-26-2015, 06:11 AM
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Started by Richard Finney, 09-26-2015, 05:22 AM
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0 responses
1,087 views
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Started by genomica, 09-24-2015, 05:47 AM
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6 responses
2,012 views
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by genomica
09-26-2015, 01:03 AM
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Started by Saeideh, 09-26-2015, 12:39 AM
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0 responses
1,145 views
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by Saeideh
09-26-2015, 12:39 AM
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Started by friducha, 07-03-2015, 03:16 PM
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5 responses
6,900 views
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by dpryan
09-25-2015, 10:03 PM
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Started by mjudkins, 09-25-2015, 06:15 PM
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0 responses
2,350 views
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by mjudkins
09-25-2015, 06:15 PM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:04 AM
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by SEQadmin2
Yesterday, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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