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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,334 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,066 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by turnersd, 03-12-2012, 12:50 PM
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33 responses
44,980 views
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by NRB
03-23-2020, 05:06 AM
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Started by CharlesG, 03-19-2020, 10:47 PM
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0 responses
2,148 views
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by CharlesG
03-19-2020, 10:47 PM
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Started by roardan, 03-19-2020, 04:37 AM
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1 response
2,285 views
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by GenoMax
03-19-2020, 06:05 PM
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Started by pwaltman, 03-19-2020, 03:19 PM
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0 responses
1,254 views
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by pwaltman
03-19-2020, 03:19 PM
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Started by polaxgr, 03-18-2020, 02:58 AM
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0 responses
1,369 views
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by polaxgr
03-18-2020, 02:58 AM
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Started by lcabus, 03-16-2020, 08:12 AM
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0 responses
1,803 views
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by lcabus
03-16-2020, 08:12 AM
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Started by yy273826987, 03-08-2020, 12:29 PM
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5 responses
2,091 views
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by kmcarr
03-11-2020, 04:55 AM
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Started by LHochman, 03-10-2020, 08:27 AM
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0 responses
2,177 views
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by LHochman
03-10-2020, 08:27 AM
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Started by jennorocks, 03-10-2020, 06:35 AM
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0 responses
1,158 views
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by jennorocks
03-10-2020, 06:35 AM
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Started by pitch_, 03-10-2020, 12:40 AM
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0 responses
1,504 views
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by pitch_
03-10-2020, 12:40 AM
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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Today, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
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Started by SEQadmin2, Yesterday, 11:05 AM
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by SEQadmin2
Yesterday, 11:05 AM
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Started by SEQadmin2, 07-02-2026, 11:08 AM
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by SEQadmin2
07-02-2026, 11:08 AM
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Started by SEQadmin2, 06-30-2026, 05:37 AM
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by SEQadmin2
06-30-2026, 05:37 AM
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