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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
105,471 views
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by Guest
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
673,290 views
1 like
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by ECO
12-25-2009, 06:45 PM
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Started by Marius, 07-08-2014, 02:11 AM
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0 responses
1,695 views
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by Marius
07-08-2014, 02:11 AM
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Started by likebiology, 07-07-2014, 07:56 AM
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3 responses
2,991 views
0 likes
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Last Post
by likebiology
07-07-2014, 11:59 PM
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Started by fjrossello, 06-30-2014, 07:45 PM
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1 response
2,168 views
0 likes
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Last Post
by fjrossello
07-07-2014, 04:07 PM
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Started by Elsie, 07-06-2014, 08:10 PM
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3 responses
1,955 views
0 likes
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Last Post
by Elsie
07-07-2014, 03:49 PM
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Started by sehrrot, 06-10-2014, 04:35 AM
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5 responses
3,761 views
0 likes
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Last Post
by kopi-o
07-07-2014, 03:20 PM
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Started by keliu.iluke, 07-07-2014, 05:47 AM
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1 response
1,245 views
0 likes
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Last Post
by davetang
07-07-2014, 03:15 PM
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Started by GuiFF, 10-19-2012, 07:01 AM
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1 response
2,078 views
0 likes
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Last Post
by millerma1
07-07-2014, 10:05 AM
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Started by Nico38, 04-29-2014, 06:57 AM
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1 response
2,333 views
0 likes
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Last Post
by millerma1
07-07-2014, 09:45 AM
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Started by Brian Bushnell, 01-22-2014, 02:57 PM
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24 responses
17,230 views
0 likes
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Last Post 07-07-2014, 09:37 AM | ||
Started by bwubb, 03-01-2012, 11:36 AM
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11 responses
10,184 views
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Last Post
by KaiYe
07-07-2014, 05:47 AM
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...-
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