modENCODE project aims to provide the biological research community with a comprehensive encyclopedia of genomic functional elements in the model organisms C. elegans and D.melanogaster. Data Coordination Center for modENCODE is conducting a series of webinars with the next one, "Understanding transcription in Drosophila sister species", scheduled on Thursday Apr 5th, 12:00 EDT (Eastern US Daylight Saving time). This webinar will discuss the data produced in Brian Oliver's lab for several Drosophila species. Space is limited so advance registration is necessary. Please email [email protected] to reserve your spot. More details and the schedule are at http://wiki.modencode.org/project/in...ility_webinars
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM