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  • Genomics for Decision Making During Drug Development and Clinical Trials

    Cambridge Healthtech Institute's Inaugural NGS for Drugs, Patients and Clinical Trials (March 21-22, 2013 in San Diego) features a series of opening discussions focused on the utilization of genomic data for decision making during drug development, including steps for discerning and validating targets, model selection, biomarker development, patient stratification and CAP/CLIA-certified operations.
    Profiling and NGS in Cancer: Challenges and Applications to Targets, Models, and Resistance
    Paul Rejto, Ph.D., Director, Computational Biology, Oncology Research Unit, Pfizer, Inc.

    Impact of Next-Generation Sequencing on Oncology Drug Discovery and Early Clinical Development
    Oleg Iartchouk, Ph.D., Lead Scientist and Lab Head, Applied Genomics, Translational and Experimental Medicine, Sanofi

    Uncovering Genetic Interactions in Tumor Cell Lines: A Workflow-Based Approach for NGS Analysis
    Benjamin J. Adamczyk, Ph.D., Scientific Account Manager, Genedata USA, Inc.

    Devising Methods for Intuitively Handling Huge Data Sets to Simplify Biomarker Discovery
    Dongliang Ge, Ph.D., Director, Bioinformatics, Gilead Sciences, Inc.

    Stratification of Clinical Trial Subjects Using Biomarkers Developed by Next-Generation Sequencing
    Brian Dougherty, Ph.D., Lead, Translational Genomics, Oncology, AstraZeneca

    From Theory to Practice: Our First Thousand Samples
    Seth D. Crosby, M.D., Director, Alliances and Partnerships, Department of Genetics, Washington University School of Medicine

    Learn more at http://www.healthtech.com/ngs-drug-development

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  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM
  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM

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