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  • jhodges
    Member
    • Nov 2012
    • 14

    #1

    Genomics for Decision Making During Drug Development and Clinical Trials

    Cambridge Healthtech Institute's Inaugural NGS for Drugs, Patients and Clinical Trials (March 21-22, 2013 in San Diego) features a series of opening discussions focused on the utilization of genomic data for decision making during drug development, including steps for discerning and validating targets, model selection, biomarker development, patient stratification and CAP/CLIA-certified operations.
    Profiling and NGS in Cancer: Challenges and Applications to Targets, Models, and Resistance
    Paul Rejto, Ph.D., Director, Computational Biology, Oncology Research Unit, Pfizer, Inc.

    Impact of Next-Generation Sequencing on Oncology Drug Discovery and Early Clinical Development
    Oleg Iartchouk, Ph.D., Lead Scientist and Lab Head, Applied Genomics, Translational and Experimental Medicine, Sanofi

    Uncovering Genetic Interactions in Tumor Cell Lines: A Workflow-Based Approach for NGS Analysis
    Benjamin J. Adamczyk, Ph.D., Scientific Account Manager, Genedata USA, Inc.

    Devising Methods for Intuitively Handling Huge Data Sets to Simplify Biomarker Discovery
    Dongliang Ge, Ph.D., Director, Bioinformatics, Gilead Sciences, Inc.

    Stratification of Clinical Trial Subjects Using Biomarkers Developed by Next-Generation Sequencing
    Brian Dougherty, Ph.D., Lead, Translational Genomics, Oncology, AstraZeneca

    From Theory to Practice: Our First Thousand Samples
    Seth D. Crosby, M.D., Director, Alliances and Partnerships, Department of Genetics, Washington University School of Medicine

    Learn more at http://www.healthtech.com/ngs-drug-development

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  • SEQadmin2
    16S/ITS Profiling vs. Shotgun Metagenomics: What Changes in Your Workflow?
    by SEQadmin2




    NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...
    Today, 06:46 AM
  • SEQadmin2
    Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
    by SEQadmin2



    Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

    Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
    ...
    10-14-2026, 09:55 AM

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