Open to all attendees, speakers, sponsors, & exhibitors of Single-Cell Sequencing at Next Generation Dx Summit are three roundtable discussions on the following key issues:
Making Single-Cell Analysis Cost Effective for Clinical Use
Moderator: James Hicks, Ph.D., Research Professor, Cancer Genomics, Cold Spring Harbor Laboratory
Finding a Needle in a Haystack: Towards Diagnosing Rare Soft Tissue Cancer Stem Cells (CSCs)
Moderator: Michael Masterman-Smith, Ph.D., Entrepreneurial Scientist, UCLA California NanoSystems Institute
Why Single-Cell Sequencing?
Moderator: Jan Vijg, Ph.D., Professor and Chairman, Genetics, Albert Einstein College of Medicine
The discussions will be held on the second day of the Single-Cell Sequencing Conference at Next Generation Dx Summit, taking place August 20-21, 2014 in Washington, DC. For full program details and to register, please visit http://www.nextgenerationdx.com/Single-Cell-Sequencing
Making Single-Cell Analysis Cost Effective for Clinical Use
Moderator: James Hicks, Ph.D., Research Professor, Cancer Genomics, Cold Spring Harbor Laboratory
- Methods for capture: What are the tradeoffs?
- Combining RNA, DNA and protein analysis
- What genomic assays are most informative?
- Can assays be certifiable?
Finding a Needle in a Haystack: Towards Diagnosing Rare Soft Tissue Cancer Stem Cells (CSCs)
Moderator: Michael Masterman-Smith, Ph.D., Entrepreneurial Scientist, UCLA California NanoSystems Institute
- Rethinking companion diagnostics for cancer to incorporate analysis of CSCs
- Current direct methodologies of CSC detection/isolatio
- Current proxy methodologies of CSC detection/isolation
- The hope and promise of single-cell assay tools and technologies
Why Single-Cell Sequencing?
Moderator: Jan Vijg, Ph.D., Professor and Chairman, Genetics, Albert Einstein College of Medicine
- Sample limitations, e.g., prenatal diagnostics and CTCs
- To study cell-to-cell variation, e.g., in tumors as well as normal tissues
- To overcome technological constraints, e.g., detecting somatic mutations
- Cell-to-cell fluctuations in gene expression can easily impair function, yet can be undetectable by measuring averages
- How many different cell types are there?
The discussions will be held on the second day of the Single-Cell Sequencing Conference at Next Generation Dx Summit, taking place August 20-21, 2014 in Washington, DC. For full program details and to register, please visit http://www.nextgenerationdx.com/Single-Cell-Sequencing