Updated rhesus macaque genome?

[sdarko]

Hi all,

I've been working with the rheMac2 assembly for the rhesus monkey and have found it to be woefully deficient in a number of regions. The rheMac2 assembly is also about 5 years old and had low (3x-5x) coverage.

This seems strange considering that the Macaque is a model organism for a number of human diseases including HIV.

Does anyone know of a newer assembly or if any groups plan on resequencing the Macaque?

Sam

[RobNorgren]

Hi all,

I've been working with the rheMac2 assembly for the rhesus monkey and have found it to be woefully deficient in a number of regions. The rheMac2 assembly is also about 5 years old and had low (3x-5x) coverage.

This seems strange considering that the Macaque is a model organism for a number of human diseases including HIV.

Does anyone know of a newer assembly or if any groups plan on resequencing the Macaque?

Sam

Hi sdarko,

My lab has been doing additional Illumina sequencing of the rhesus reference animal. I am working with several groups to produce a new, improved assembly.

Rob Norgren