Hi all, I am a bigginner at computational genomics. Could you please tell me what "phase" means in genomics?
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Moving this to general as it's a very basic genetics question.
Briefly, phase describes whether alleles at different loci are present on the same parental chromosome (or not).
http://en.wikipedia.org/wiki/Haplotype is a good place to start.
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...-
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