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Dear all,
I am looking for a way to test for cross-over events in bacteria using microsatellite data. I could use a "four-gamete test" but this might not be a good idea because of the infinite-sites assumption. There are also a number of programs available that would perform this test on sequence data (e.g. DNaSP), however, no one has done it with microsatellites. I'm guessing this is because, in most organisms, microsatellite loci commonly occur on different chromosomes, so they won't be able to tell you anything about cross-over events. However in a bacterium with a single chromosome, microsatellites could provide information about cross-over events.
Any ideas?
I am looking for a way to test for cross-over events in bacteria using microsatellite data. I could use a "four-gamete test" but this might not be a good idea because of the infinite-sites assumption. There are also a number of programs available that would perform this test on sequence data (e.g. DNaSP), however, no one has done it with microsatellites. I'm guessing this is because, in most organisms, microsatellite loci commonly occur on different chromosomes, so they won't be able to tell you anything about cross-over events. However in a bacterium with a single chromosome, microsatellites could provide information about cross-over events.
Any ideas?