I just tried to determine miRNA features, I computed most but I still don't know how to compute the structure features like the stem length, base paring probability, largest bulge, gap ratio,,etc I tried to get my answer with the Vienna package but I couldn't. What do you suggest. Actually, I tried to extract all the possible features of the secondary structure of miRNA, I used perl and Bioperl but I didn't find any function or package to help me to get the stem length, base paring probability, largest bulge, gap ratio..etc
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM