Genapsys Raises $37M to Commercialize Next Generation Sequencing Platform

[Genohub]

"Nano-electronic" sequencer whose goal is to achieve 1kb reads by reading changes in both pH and temperature: http://venturebeat.com/2013/11/14/yu...into-genapsys/

- Genohub

[Richard Finney]

Any specifics on the technology?

Illumina has a 12 billion market cap and a significant lead.

[Genohub]

Not many specifics:

"The "Gene Electronic Nano-Integrated Ultra-Sensitive" (GENIUS) platform is based on innovative technologies to provide significant improvements in cost, accuracy, read length, throughput and ease of use relative to current state-of-art systems. The overall goal is to develop a sequencing system using nano-magnetic-electronic platforms. We are proposing a system that integrates sample preparation and enrichment steps with the sequencing module. Sample preparation will rely on a re-usable magnetic-electronic chip and a novel emulsion-free amplification method. After amplification, enrichment of template carrying monoclonal beads is achieved through 'sorting' based on DNA charge. Beads are then transferred and held on a micromagnet array integrated with a sequencing sensor chip consisting of high-density arrays of CMOS-based nano-electronic sensors for direct detection of extension reactions. "

Here are a couple links to their NIH grants:

LOW COST SEQUENCING WITH RE-USABLE MAGNETIC ARRAYS AND NANOELECTRONIC SENSORS

FABRICATION OF A DUAL NANO-BIOSENSOR FOR ACCURATE SENSITIVE AND INEXPENSIVE ELEC

- Genohub

[AllSeq]

Any specifics on the technology?

Illumina has a 12 billion market cap and a significant lead.

We've been keeping track of them over in our 'Emerging Technologies' section of the NGS Knowledge Bank: http://allseq.com/knowledgebank/emer...gies/genapsys/